Jing Leng Selected Research

Neoplasms (Cancer)

5/2024	Disruption of NADPH Homeostasis by Total Flavonoids from Adinandra nitida Merr. ex Li Leaves Triggers ROS-Dependent p53 Activation Leading to Apoptosis in Non-Small Cell Lung Cancer Cells.
1/2024	Expression patterns of E2Fs identify tumor microenvironment features in human gastric cancer.
7/2023	Dihydrotanshinone Triggers Porimin-Dependent Oncosis by ROS-Mediated Mitochondrial Dysfunction in Non-Small-Cell Lung Cancer.
1/2022	Improved Aitongxiao prescription (I-ATXP) induces apoptosis, cell cycle arrest and blocks exosomes release in hepatocellular carcinoma (HCC) cells.
10/2021	Low-dose mono(2-ethylhexyl) phthalate promotes ovarian cancer development through PPARα-dependent PI3K/Akt/NF-κB pathway.
1/2021	Platycodin D suppresses cisplatin-induced cytotoxicity by suppressing ROS-mediated oxidative damage, apoptosis, and inflammation in HEK-293 cells.
7/2020	The ethyl acetate extraction of Pileostegia tomentella (ZLTE) exerts anti-cancer effects on H1299 cells via ROS-induced canonical apoptosis.
3/2020	Benzo(a)pyrene regulated A549 cell migration, invasion and epithelial-mesenchymal transition by up-regulating long non-coding RNA linc00673.
5/2019	Characterization of Exosomes in Plasma of Patients with Breast, Ovarian, Prostate, Hepatic, Gastric, Colon, and Pancreatic Cancers.
9/2018	Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways.

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Jing Leng Research Topics

Disease

27	Neoplasms (Cancer) 05/2024 - 03/2004
11	Inflammation (Inflammations) 09/2023 - 02/2016
10	Hepatocellular Carcinoma (Hepatoma) 10/2014 - 09/2003
6	Neoplasm Metastasis (Metastasis) 09/2022 - 01/2009
5	Infections 01/2024 - 05/2016
5	Insulin Resistance 04/2019 - 01/2012
5	Cholangiocarcinoma 08/2015 - 02/2004
4	Lung Neoplasms (Lung Cancer) 07/2023 - 05/2014
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2020 - 05/2014
3	Diabetes Mellitus 01/2023 - 01/2019
3	Liver Neoplasms (Liver Cancer) 01/2023 - 09/2003
3	Carcinoma (Carcinomatosis) 01/2022 - 02/2006
3	Alcoholic Fatty Liver 01/2022 - 01/2018
3	Body Weight (Weight, Body) 04/2019 - 08/2004
2	Chronic Obstructive Pulmonary Disease (COPD) 05/2024 - 05/2024
2	Carcinogenesis 07/2022 - 06/2013
2	Endotoxemia 01/2022 - 01/2020
2	Hypoxia (Hypoxemia) 01/2021 - 08/2014
2	Non-alcoholic Fatty Liver Disease 01/2020 - 01/2018
2	Chemical and Drug Induced Liver Injury 01/2019 - 11/2018
2	Wounds and Injuries (Trauma) 01/2019 - 12/2012
2	Atherosclerosis 01/2019 - 01/2017
2	Necrosis 12/2018 - 11/2018
2	Hyperlipidemias (Hyperlipidemia) 01/2017 - 02/2016
2	Overactive Urinary Bladder (Overactive Bladder) 01/2017 - 10/2016
2	Glucose Intolerance 01/2017 - 02/2016
2	Type 2 Diabetes Mellitus (MODY) 01/2014 - 12/2012
2	Hypersensitivity (Allergy) 09/2012 - 06/2012
1	Orthomyxoviridae Infections 01/2024
1	Stomach Neoplasms (Stomach Cancer) 01/2024
1	Stress Urinary Incontinence 07/2023
1	Huntington Disease (Huntington's Disease) 01/2023
1	Acute Kidney Injury (Acute Renal Failure) 01/2023
1	Ischemia 01/2023
1	Sarcopenia 01/2023
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Virus Diseases (Viral Diseases) 01/2022
1	Hypertension (High Blood Pressure) 12/2021
1	Pre-Eclampsia (Preeclampsia) 12/2021
1	Neuroinflammatory Diseases 12/2021

Drug/Important Bio-Agent (IBA)

14	Dinoprostone (PGE2)FDA Link 01/2019 - 11/2007
13	ProstaglandinsIBA 01/2023 - 09/2003
10	Proteins (Proteins, Gene)FDA Link 07/2023 - 10/2005
7	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 09/2018 - 09/2003
4	RNA (Ribonucleic Acid)IBA 05/2024 - 05/2019
4	Therapeutic UsesIBA 05/2024 - 10/2016
4	SaponinsIBA 01/2021 - 09/2018
4	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2019 - 11/2018
4	Celecoxib (Celebrex)FDA Link 10/2005 - 09/2003
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2023 - 10/2016
3	Cisplatin (Platino)FDA LinkGeneric 09/2023 - 09/2018
3	CytokinesIBA 01/2023 - 01/2014
3	Biomarkers (Surrogate Marker)IBA 09/2022 - 05/2019
3	LipopolysaccharidesIBA 01/2022 - 08/2017
3	Mitogen-Activated Protein KinasesIBA 01/2021 - 11/2007
3	Glucose (Dextrose)FDA LinkGeneric 04/2019 - 08/2004
3	Insulin (Novolin)FDA Link 01/2017 - 01/2014
3	IntegrinsIBA 09/2016 - 05/2014
3	Prostaglandins EIBA 03/2013 - 02/2004
2	Caspase 3 (Caspase-3)IBA 05/2024 - 12/2018
2	MicroRNAs (MicroRNA)IBA 01/2024 - 01/2023
2	Messenger RNA (mRNA)IBA 01/2024 - 10/2005
2	Eosine Yellowish-(YS) (Eosin)IBA 07/2023 - 01/2023
2	Hematoxylin (Haematoxylon)IBA 07/2023 - 01/2023
2	Long Noncoding RNAIBA 09/2022 - 03/2020
2	Carrier Proteins (Binding Protein)IBA 07/2022 - 03/2013
2	geniposideIBA 01/2022 - 01/2018
2	Chlorogenic AcidIBA 01/2022 - 01/2018
2	Streptozocin (Streptozotocin)FDA Link 09/2020 - 01/2014
2	qushi huayuIBA 01/2020 - 01/2018
2	DNA (Deoxyribonucleic Acid)IBA 05/2019 - 01/2017
2	Tolterodine Tartrate (Detrol)FDA Link 01/2017 - 09/2010
2	HLA-DR Antigens (HLA-DR)IBA 10/2016 - 05/2016
2	Trichloroethylene (Trichloroethene)IBA 03/2015 - 12/2012
2	TabletsIBA 07/2013 - 10/2007
2	Focal Adhesion Protein-Tyrosine KinasesIBA 05/2013 - 01/2009
2	ChromatinIBA 09/2012 - 06/2012
1	Herbal TeasIBA 05/2024
1	Antiviral Agents (Antivirals)IBA 01/2024
1	E2F Transcription FactorsIBA 01/2024
1	LuciferasesIBA 01/2024
1	Adenosine Triphosphate (ATP)IBA 07/2023
1	Ammonium CompoundsIBA 01/2023
1	C-PeptideIBA 01/2023
1	ethyl 6- (N- (2- chloro- 4- fluorophenyl)sulfamoyl)cyclohex- 1- ene- 1- carboxylateIBA 01/2023
1	PhosphoserineIBA 07/2022
1	Fluorouracil (Carac)FDA LinkGeneric 01/2022
1	EndotoxinsIBA 01/2022
1	Polysaccharides (Glycans)IBA 01/2022
1	acceleratory factor from growth hormone (AcG)IBA 01/2022
1	Pyridostigmine Bromide (Pyridostigmine)FDA LinkGeneric 12/2021
1	AcetylcholinesteraseIBA 12/2021
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 12/2021
1	mono-(2-ethylhexyl)phthalateIBA 10/2021

Therapy/Procedure

7	Chinese Traditional Medicine (Traditional Chinese Medicine) 05/2024 - 07/2013
6	Therapeutics 05/2024 - 10/2016
2	Aftercare (After-Treatment) 02/2021 - 08/2004
2	Chemoprevention 09/2017 - 03/2013
1	Ablation Techniques 05/2024
1	Prostatectomy (Retropubic Prostatectomy) 07/2023